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    Penn State vs. Northwestern odds, line, spread: Proven model reveals college football picks, predictions for Week 5, 2022

    The SportsLine projection model has a pick for the clash between Northwestern and Penn State. Here are the results:
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    A Big Ten battle is on tap between the No. 11 Penn State Nittany Lions and the Northwestern Wildcats at 3:30 p.m. ET on Saturday at Beaver Stadium. Penn State is looking to stay unbeaten, as it has won its first four games of the season. The Nittany Lions are favored by 26 points in the latest Penn State vs. Northwestern odds from Caesars Sportsbook, while the over/under is set at 52. 

    Before you make any Northwestern vs. Penn State picks, you'll want to see the college football predictions from the SportsLine Projection Model.

    The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

    Now, it has simulated Penn State vs. Northwestern 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in almost 60% of simulations. You absolutely need to see it before locking in your own picks.

    So who wins Penn State vs. Northwestern? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!

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    SportsLine Staff

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