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Drake Maye and the New England Patriots aim to bounce back after a lackluster loss to the Jaguars, but it won't be easy traveling to Buffalo to face Josh Allen and the Bills in an AFC East Week 4 matchup. The Patriots (1-2) got dismantled 35-6 in Jacksonville in Week 3 but they still have a defense that ranks fifth in yards allowed. The Bills (3-0) has simply outscored all their opponents, averaging an NFL-best 33.7 ppg. Claim the latest Polymarket promo code SPORTSLINE to get a $50 trading bonus after a $10 deposit:
Kickoff is set for 1 p.m. ET from Highmark Stadium in Orchard Park, N.Y. The latest Patriots vs. Bills odds have Buffalo as a 7-point favorite. The over/under for total points scored is 48.5. Buffalo is one of three teams with a 3-0 mark against the spread.
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