The San Diego Padres (55-44) and the Detroit Tigers (39-59) wrap up their three-game series on Wednesday, with the first pitch set for 1:10 p.m. ET. San Diego is listed as a -140 favorite (risk $140 to win $100) on the money line in the latest Padres vs. Tigers odds from Caesars Sportsbook, while the over-under for total runs scored is 7 (see up-to-date odds for every game this week on our MLB odds page).

Before making any Padres vs. Tigers picks, you NEED to check out the MLB predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it is 284-243 on top-rated MLB money-line picks since the start of the 2021 season, returning over $400 for $100 players. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen profitable returns.

The model knows San Diego third baseman Manny Machado has been a stud on both sides of the ball. Machado has superb bat speed and amazing pop in his swing. The six-time All-Star is able to push the ball to all parts of the diamond while also being a sure-handed defender in the corner. He's leading the team in batting average (.301), home runs (16), and RBI (54). 

The model also knows Detroit infielder Harold Castro is a nice offensive piece. Castro makes consistent contact with the ball thanks to his quick hands and solid pitch recognition skills. The 28-year-old has been playing good ball lately, and he looks to continue that. Castro is currently on a 10-game hitting streak, going 2-for-5 with a double in his last game.

Now, the model has set its sights on Padres vs. Tigers. We can tell you the model is leaning over the total, and it also says one side of the money line has ALL the value. You ABSOLUTELY need to see it before locking in any MLB picks.

So who wins Padres vs. Tigers? And which side of the money line has ALL the value? Join SportsLine here to find out, all from the model that has crushed its top-rated MLB money-line picks!