The San Diego Padres and Philadelphia Phillies clash in Game 3 of the National League Championship Series on Friday. The Phillies (87-75) and Padres (89-73) split their two games in San Diego with the Phillies winning Game 1 2-0 and the Padres taking Game 2 8-5. San Diego is looking to reach its first World Series since 1998, while Philadelphia hasn't been to one since 2009. 

First pitch from Citizens Bank Park in Philadelphia is set for 7:37 p.m. ET. San Diego is listed as a -20 favorite (risk $120 to win $100) on the money line in the latest Padres vs. Phillies odds from Caesars Sportsbook, while the over/under for total runs scored is 7.5. (see the latest lines for every game on our MLB odds page).

Before making any Padres vs. Phillies picks, you NEED to see the latest MLB predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it enters the league championship round on a 20-13 roll on top-rated MLB money-line picks, returning more than $400. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen HUGE returns!

The model knows San Diego third baseman Manny Machado was a difference-maker in Game 2, going 3-for-5 with a home run. In nine postseason games this year, Machado has four multi-hit games already, with three homers and six RBI. He was a big reason for San Diego's success against the Dodgers in the NLDS, going 5-for-14 (.357) with a double, homer and two RBI. He has flexed some power against Philadelphia, hitting three doubles, one triple and eight homers in 26 regular-season games against the Phillies.

The model also knows Philadelphia is led by slugger Bryce Harper, who has been on fire. He has at least two hits in five of eight postseason games with four doubles, four homers and seven RBI. He homered in Game 1 of the NLCS vs. the Padres and was 2-for-4 with a double in Game 2. In 45 career regular-season games against San Diego, Harper is hitting .300 with four doubles, two triples, 12 homers and 39 RBI.

Now, it has set its sights on Padres vs. Phillies. We can tell you the model is leaning Over on the total, and it also says one side of the money line has ALL the value! You ABSOLUTELY need to see it before locking in any MLB picks of your own.

So who wins Game 3 of Padres vs. Phillies? And which side of the money line has ALL the value? ... Join SportsLine right now to find out which side of the Padres vs. Phillies run line you should be all over on Friday, all from the model on a roll on MLB picks!