The San Diego Padres (30-19) and the St. Louis Cardinals (28-21) wrap up their three-game series on Wednesday afternoon, with the first pitch set for 1:15 p.m. ET. San Diego is listed as the -125 favorite (risk $125 to win $100) at Caesars Sportsbook, while St. Louis is set as the +105 underdog. The over-under for total runs expected is set at 8 (see up-to-date odds for every game this week on our MLB odds page).

Before making any Padres vs. Cardinals picks, you NEED to check out the MLB predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a strong start to the 2022 season. It's on a 48-31 roll on top-rated MLB money-line picks through eight weeks, returning over $1,100 for $100 players. Anyone following it has seen HUGE returns!

The model knows San Diego first baseman Eric Hosmer is a strong presence in the lineup. Hosmer has a nice left-handed stroke with the power to drive the ball into any gap. He also plays stout defense at the corner. Hosmer is a four-time Gold Glove Winner. He has a batting average of .312 with four home runs and 24 RBIs. 

The model also knows St. Louis center fielder Harrison Bader has amazing speed in the outfield. The 27-year-old is on a roll and is currently on a seven-game hitting streak. Bader's batting average is .255 along with four homers and 15 runs driven in. On May 27, he went 2-for-3 with two singles and one run scored. 

Now, the model has set its sights on Padres vs. Cardinals. We can tell you the model is leaning Under the total, and it also says one side of the money line has ALL the value. You ABSOLUTELY need to see it before locking in any MLB picks.

So who wins Padres vs. Cardinals? And which side of the money line has ALL the value? Join SportsLine here to find out, all from the model that has crushed its top-rated MLB money-line picks!