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Notre Dame vs. BYU odds, line, spread: Proven model reveals college football picks, predictions for Week 6, 2022

SportsLine's projection model generated CFB picks, predictions, and best bets for BYU Cougars and Notre Dame Fighting Irish
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An FBS Independents battle is on tap between the Notre Dame Fighting Irish and the BYU Cougars at 7:30 p.m. ET on Saturday at Allegiant Stadium. BYU is 4-1 while Notre Dame is 2-2. The Fighting Irish are favored by 3.5 points in the latest Notre Dame vs. BYU odds from Caesars Sportsbook and the over/under is set at 51.5. Before you make any BYU vs. Notre Dame picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Notre Dame vs. BYU 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick where one side has all the value. You absolutely need to see it before locking in your own picks.

So who wins Notre Dame vs. BYU? And which side of the spread has all the value? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!

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SportsLine Staff

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