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NFL Week 4 Cardinals vs. Rams line, odds: Predictions, spread picks for Sunday's NFC West showdown from advanced computer model

The SportsLine Projection Model has simulated the Week 4 game between Arizona and Los Angeles 10,000 times and revealed its results

By@SportsLineUpdated: Oct 03, 2021 7:07PM UTC . 3 min read

It's a battle for the top of the NFC West on Sunday afternoon when the Los Angeles Rams (3-0) host the Arizona Cardinals (3-0) in an NFL Week 4 matchup at SoFi Stadium. Kickoff is set for 4:05 p.m. ET. Los Angeles is a 3.5-point favorite in the latest Cardinals vs. Rams odds from Caesars Sportsbook, while the Over-Under is 54.

Before you make any Cardinals vs. Rams picks, you NEED to check out the latest NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up almost $7,900 for $100 players on top-rated NFL picks since its inception six years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters Week 4 of the 2021 season on an incredible 123-81 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the Top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

The model's projections take into account that the Rams have looked like one of the NFC's best teams with Matthew Stafford at quarterback. The former Lions star has 942 passing yards and nine touchdowns with just one interception in his first three games with L.A. Cooper Kupp has 25 receptions for a league-high 367 yards and has scored five times, while fellow receiver Robert Woods and tight end Tyler Higbee have 11 catches apiece.       

The model also considered the impact Cardinals quarterback Kyler Murray is having this season. The third-year pro ranks third in the league with 1,005 passing yards and has seven TD passes but has thrown four interceptions. He has involved numerous receivers, but running back Chase Edmonds leads the team with 16 catches. Christian Kirk has 15 for 239 yards, and Rondale Moore and DeAndre Hopkins each have 13 and more than 150 yards.         

Now, the model has locked in on the Cardinals vs. Rams matchup and revealed its selections. We can tell you it's leaning Under the total, and it also says one side of the spread has all the value! You ABSOLUTELY need to see it before locking in any NFL picks of your own.

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