NFL football pool, pick'em, office pool, confidence picks for Week 16, 2022: Back the 49ers

The Cleveland Browns will be trying to keep their playoff hopes alive when they face the New Orleans Saints on Saturday afternoon. Cleveland has won three of its last four games, including a 13-3 win over Baltimore last week. The Browns are 3-point favorites in the Week 16 NFL odds at Caesars Sportsbook. Before making any Week 16 NFL office pool picks, you NEED to see which teams the SportsLine Projection Model is backing in its NFL football pool picks.

The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 16 of the 2022 NFL season on an incredible 157-113 run on top-rated NFL picks that dates back to the 2017 season.  

The model ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP.  

In Week 16, we can tell you the model is extremely high on the San Francisco 49ers defeating the Washington Commanders. In fact, the model is projecting a 27-17 win for the 49ers, who get up the straight-up victory in 75% of simulations.

The model is also calling for several favorites to struggle more than expected and several surprising teams to hang tough! Picks like those can give you a HUGE edge in your pools. You ABSOLUTELY need to see which team the model is backing before locking in your NFL office pool picks!

So which teams win outright in Week 16? And which underdogs should you back? ... Join SportsLine right now to see the optimal NFL office pool picks, all from the model that consistently crushes the NFL and has ranked in the top 10 on NFLPickWatch four of the past six years!