Week 3 of the 2023 NFL season begins with a star-studded showdown between the New York Giants and San Francisco 49ers on Thursday Night Football. There will be no shortage of elite players in the NFL DFS player pool, including Christian McCaffrey, Deebo Samuel, Brandon Aiyuk and Daniel Jones. Before setting your NFL DFS lineups for 49ers vs. Giants, you NEED to see what Mike McClure has to say.

McClure is a legendary professional DFS player with over $2 million in career winnings. He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine. His methodology has led to enormous cashes on FanDuel and DraftKings.

He took down two high-stakes tournaments on FanDuel in 2020 and recorded a pair of top-10 finishes in tournaments with over 130,000 entrants on DraftKings. His lineups also finished inside the top 1 percent in more than a dozen other tournaments. Last year, he won the DraftKings Millionaire Maker twice and the FanDuel Million once.

We can tell you 49ers running back Christian McCaffrey is one of McClure's top NFL DFS picks for Thursday Night Football. Part of McClure's optimal NFL DFS strategy also includes rostering Giants tight end Darren Waller, who had six receptions for 76 yards last week.

McClure is also targeting a player who could go off for MASSIVE numbers on Thursday Night Football! This pick could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who it is before locking in any lineups.

What are the top NFL DFS picks for Giants vs. 49ers on Thursday Night Football, and which player is a MUST-ROSTER? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NFL DFS!