Teams trending in opposite directions meet when the Washington Nationals battle the New York Mets in a key National League East matchup on Thursday afternoon. The Nationals (30-37), who have lost seven of nine, are 15-19 on the road this season. The Mets (44-24), who have won five in a row, are 26-7 on their home field in 2025.

First pitch from Citi Field in New York is set for 1:10 p.m. ET. The Mets have won eight of the past 10 meetings with the Nationals. New York is a -231 favorite on the money line (risk $231 to win $100) in the latest Nationals vs. Mets odds from DraftKings Sportsbook, while the total number of runs Vegas thinks will be scored, or the over/under, is 8 in the latest MLB odds. 

Before you make any Nationals vs. Mets picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 12 of the 2025 MLB season on a 27-23 run on top-rated MLB sides picks. It has excelled making home run prop picks, returning more than 35 units of profit over the past two months. Anybody following could have seen strong returns!

The model has simulated Nationals vs. Mets 10,000 times and the results are in. We can tell you the model is going Over on the run total, and it also says one side of the money line has all the value!

Who wins Nationals vs. Mets, and which side of the money line has all the value? ... Join SportsLine right now to find out which side of the money line you should be all over, all from the model on a 27-23 roll on top-rated MLB picks!