Gerrit Cole takes the mound looking to stop the Yankees' two-game skid when the New York Yankees host the Baltimore Orioles on Monday at Yankee Stadium in the Bronx, N.Y. The Yankees (29-12) own the best record in baseball but dropped a doubleheader to the White Sox on Sunday. 

New York is a heavy -310 money-line favorite in the latest Yankees vs. Orioles odds from Caesars Sportsbook, while Baltimore is a +255 underdog. First pitch is set for 7:05 p.m. ET. The game is one of 12 on the MLB schedule on Monday. (See up-to-date lines for every game on our MLB odds page.)

Before making any MLB picks or parlays, be sure to see the MLB predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a strong start to the 2022 season. It's on a 41-30 roll on top-rated MLB money-line picks through seven weeks, returning almost $600 for $100 players. Anyone following it has seen HUGE returns.

Now, the model has set its sights on the MLB schedule for Monday, May 23. Using its top picks for the day, the model has generated a four-leg parlay that would pay well over 26-1. The parlay doesn't start until 6:35 p.m. ET, giving you plenty of time to make your MLB picks.

We can tell you that one of the picks is the A's (+150) to beat the Mariners. But the model has three other picks, including a play on an underdog who wins outright almost 60 percent of the time! You ABSOLUTELY need to see them before locking in any MLB picks of your own.

So which big AL underdog is a MUST-BACK? And what other teams do you need to include in your parlay for a payout of 26-1? ... Join SportsLine right now to find out which picks you should be all over on Monday, all from the model that is on a 41-30 roll on top-rated MLB moneyline picks through seven weeks!