The Pittsburgh Pirates attempt to end their four-game losing streak when they visit the San Diego Padres for the opener of a three-game series at 10:10 p.m. ET on Monday. San Diego is the -180 favorite (risk $180 to win $100) at William Hill Sportsbook, while the Over-Under for total runs scored is eight in the latest Pirates vs. Padres odds. The game is one of 10 on the MLB schedule for Monday. (See up-to-date lines for every game on our MLB odds page.)

Before making any MLB picks for that game or others in the evening, you NEED to see the latest predictions from the SportsLine Projection Model.

This model, which simulates every pitch of every game 10,000 times, had a banner 2019 season, the league's last full schedule, returning more than $1,400 on its top-rated money-line and run-line picks. It is off to a profitable start in 2021, going 29-21 on top-rated MLB money-line picks, returning over $250! Anyone following it has seen HUGE rewards.

Now, the model has set its sights on the MLB schedule for Monday. Using its top picks for the day, the model has generated a four-leg parlay that would pay almost 12-1! The best part is that it doesn't start until 7:05 p.m. ET, so you have plenty of time to enter your picks!

One of the MLB picks the model loves for Monday: The San Francisco Giants (+110) win against the Colorado Rockies. The model also has three other picks, including a MUST-SEE underdog that pays plus-money! You ABSOLUTELY need to see it before locking in any MLB picks of your own.

So what significant underdog is strong value on Monday? And what other teams do you need include in your parlay for a HUGE payout of almost 12-1? ... Join SportsLine right now to find out which picks you should be all over on Monday, all from the model that was up more than $1,400 on MLB picks in 2019!