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The Missouri State Bears open Conference USA play when they battle the Western Kentucky Hilltoppers Thursday night on CBS Sports Network. Missouri State is coming off a 34-24 loss at SMU on Sept. 26, while Western Kentucky dropped a 34-13 decision at New Mexico State on Oct. 1. The Bears (1-3, 0-0 C-USA), who have lost two in a row, are 0-2 on the road this season. The Hilltoppers (1-4, 0-1 C-USA), who have been outscored 198-99 on the year, are 1-0 on their home field in 2026. Western Kentucky leads the all-time series 9-2, including nine straight wins in the series. Claim the latest Polymarket promo code SPORTSLINE to get a $25 trading bonus after a $10 deposit:
Kickoff is set for 7 p.m. ET at Houchens Industries-L.T. Smith Stadium in Bowling Green, Ky. The Hilltoppers are 2.5-point favorites, with the over/under at 56.5 in the latest Missouri State vs. Western Kentucky odds.
Before making any Missouri State vs. Western Kentucky picks, check out the college football predictions from the SportsLine Projection Model.
The model simulates every FBS game 10,000 times. It entered Week 6 on a profitable 40-35 run on all top-rated college football picks! Anybody following could have seen strong returns!
The model has simulated Missouri State vs. Western Kentucky 10,000 times and the results are in. The model is going Over on the total, and it also says one side of the spread hits nearly 60% of the time!
So who wins Missouri State vs. Western Kentucky, and which side of the spread hits nearly 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that is on a 40-35 run on top-rated CFB picks!
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Written by Daniel Kohn
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