Michigan vs. Purdue odds, line: 2023 college football picks, Week 10 predictions from proven model

The No. 3 Michigan Wolverines will try to avoid getting caught up in distractions caused by a signal-stealing scandal when they host the Purdue Boilermakers on Saturday night. Michigan improved to 8-0 with a 49-0 win against Michigan State two weeks ago before having a bye last week. Purdue has lost five of its last six games, including a 31-14 loss at Nebraska its last time out. 

Kickoff is set for 7:30 p.m. ET on Saturday at Michigan Stadium. Michigan is favored by 32.5 points in the latest Michigan vs. Purdue odds, while the over/under is set at 53 points, per SportsLine consensus. 

Before entering any Purdue vs. Michigan picks, you NEED to see the college football predictions from the model at SportsLine.

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The model has simulated Michigan vs. Purdue 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in nearly 60% of simulations. You can only see the pick at SportsLine.

So who wins Purdue vs. Michigan? And which side of the spread is hitting nearly 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!