The Michigan Wolverines look to build some momentum in the Big Ten on Wednesday evening when they host the Northwestern Wildcats. Tip-off from the Crisler Center is set for 6:30 p.m. ET, where the Wolverines have won five of their seven home games this season. The Wildcats are just 2-3 on the road this season and have won just once in their last seven games. Northwestern beat Michigan at home in their first matchup of the 2020-21 season, but lost at the Crisler Center two weeks later in their last meeting.

The Wolverines are favored by eight points in the latest Michigan vs. Northwestern odds from Caesars Sportsbook, and the over-under is set at 138.5. Before you make any Northwestern vs. Michigan picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. It enters Week 12 of the season with a 49-36 record on all top-rated college basketball picks, returning almost $700. Over the past five-plus years, the proprietary computer model has generated an impressive profit of $2,800 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

Now, it has simulated Michigan vs. Northwestern 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in just over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

Who wins Michigan vs. Northwestern? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks ... If you're already a member, see the picks below!