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Michigan State vs. Nebraska odds, line, spread: Proven model reveals college football picks, predictions for Week 4, 2021

The SportsLine projection model has a pick for the clash between Nebraska and Michigan State.
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A Big Ten battle between Michigan State and Nebraska is set to go off at 7 p.m. ET on Saturday at Spartan Stadium. The Spartans have already won more games than they did in all of 2020, but Nebraska appears to have improved each week since the start of the season.

Michigan State is 3-0 overall and 1-0 at home, while Nebraska is 2-2 overall and 0-2 on the road. The Spartans are favored by five points in the latest Michigan State vs. Nebraska odds from Caesars Sportsbook, and the over-under is set at 51.5. The Spartans have the eleventh-best rushing offense in the country, while the Huskers allow 4.34 yards per carry from opposing rushers and allow more than 156 yards on the ground per game. Nebraska quarterback Adrian Martinez has the third-most yards from scrimmage among all FBS players.

Before you make any Nebraska vs. Michigan State picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. It also enters Week 4 of the 2021 season on a 72-58 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, it has simulated Michigan State vs. Nebraska 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Michigan State vs. Nebraska? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks ... If you're already a member, see the picks below!

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SportsLine Staff