Memphis vs. East Carolina odds, line, spread: Proven model reveals college basketball picks, predictions for Jan. 27, 2022

An American Athletic battle is on tap between the Memphis Tigers and the East Carolina Pirates at 9 p.m. ET on Thursday at FedExForum. Memphis is 10-8 overall and 7-2 at home, while East Carolina is 11-7 overall and 0-3 on the road. The Tigers are ranked seventh in the American Athletic; East Carolina is ranked eighth. 

The Tigers are favored by 13 points in the latest Memphis vs. East Carolina odds from Caesars Sportsbook, while the over-under is set at 148.5. Before you make any East Carolina vs. Memphis picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. It enters Week 12 of the season with a 49-36 record on all top-rated college basketball picks, returning almost $700. Over the past five-plus years, the proprietary computer model has generated an impressive profit of $2,800 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Memphis vs. East Carolina 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Memphis vs. East Carolina? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.