The Louisiana Ragin' Cajuns host the Eastern Michigan Eagles at 7 p.m. ET on Saturday at Cajun Field. Louisiana started its season with a win against Southeastern Louisiana last weekend. After a seven-win season last year, Eastern Michigan opened things with a win in Week 1 against Eastern Kentucky. The Ragin' Cajuns got off to a good start in the post-Billy Napier era with 374 yards of offense in their season-opener.

The Ragin' Cajuns are favored by 11.5 points in the latest Louisiana vs. Eastern Michigan odds from Caesars Sportsbook, and the over/under is set at 56.5. Before you make any Eastern Michigan vs. Louisiana picks, you MUST see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,500 for $100 players on its top-rated college football picks against the spread. It enters Week 2 of the 2022 college football season on a 48-37 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen HUGE returns.

Now, it has simulated Louisiana vs. Eastern Michigan 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50% of all simulations. You absolutely NEED to see it before locking in your own picks.

Who wins Louisiana vs. Eastern Michigan? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks ... If you're already a member, see the picks below!