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Teams that can score a lot of points clash when the Detroit Lions take on the Carolina Panthers in a key NFC showdown on 'Sunday Night Football.' Detroit outlasted the New York Jets 31-24 in Week 3, while Carolina fell short 21-18 against the Cleveland Browns. The Lions (2-1), who are averaging 31 points per game, are giving up 31.7 and are 0-1 on the road. The Panthers (1-2), who are averaging 29.7 points, have allowed 27.7 and are 0-1 on their home field. Carolina will be without several players, including cornerback Jaycee Horn (quad). Claim the latest Polymarket promo code SPORTSLINE to get a $50 trading bonus after a $10 deposit:
Kickoff is at 8:20 p.m. ET from Bank of America Stadium in Charlotte, N.C. The latest Lions vs. Panthers odds have Detroit as a 3.5-point favorite, while the over/under for total points scored is 50.5. The Lions are 3-7 ATS over their past 10 games, while the Panthers are 5-5.
Before making any Lions vs. Panthers picks, or 'Sunday Night Football' predictions of your own, you NEED to see what SportsLine expert Larry Hartstein has to say.
A former lead writer for Covers and The Linemakers, Hartstein combines a vast network of Vegas sources with an analytical approach he honed working for Pro Football Focus. He is coming off a 2025 NFL season in which he went 50-37 ATS (57.5 percent), putting him at 643-555 ATS all time. For NFL Office Pool players, Hartstein picked every game straight-up the past two seasons and nailed nearly 70 percent of those picks. He enters this season on a 22-11-1 roll on his last 34 picks involving the Lions, returning $966 to $100 players! Anyone following his picks could have seen huge returns.
Now, Hartstein has locked in another confident pick for Lions vs. Panthers.
He's leaning Over the point total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.
So who wins Lions vs. Panthers on Sunday night, and what x-factor makes one side of the spread hit HARD? ... Join SportsLine RIGHT NOW to see which side of the Lions vs. Panthers line to back, all from the expert who has returned $966 to $100 players in his last 34 picks involving the Lions!
Don't miss out: All new SportsLine memberships include Paramount+ Premium -- a $13.99/month value -- for no extra cost! Join now and get it all.
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Written by Daniel Kohn
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