Lions vs. Packers odds, line, spread: Proven model reveals NFL picks, predictions for Week 18, 2022

An NFC North battle is on tap between the Detroit Lions and the Green Bay Packers at 1 p.m. ET on Sunday at Ford Field. Detroit is 2-13-1 overall and 2-5 at home, while Green Bay is 13-3 overall and 5-3 on the road. 

Green Bay is favored by 3.5 points in the latest Packers vs. Lions odds from Caesars Sportsbook, and the over-under is set at 44.5. Before you make any Packers vs. Lions picks and predictions, you'll want to see what the SportsLine Projection Model is saying.  

The model, which simulates every NFL game 10,000 times, is up over $7,200 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 18 of the 2021 season on an incredible 135-96 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

Now, it has simulated Lions vs. Packers 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also has generated a pick that hits in 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Lions vs. Packers? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks... If you're already a member, see the picks below!