The Los Angeles Lakers (1-2) got their first win of the season last week in a close matchup against the Memphis Grizzlies and could improve .500 with a second victory on Tuesday. The 2019-20 NBA champions will face the San Antonio Spurs (1-2) at the AT&T Center in their fourth game of the season. Lebron James (ankle) is questionable for the Lakers. 

Caesars Sportsbook lists the Lakers as 2.5-point favorites, and the Over-Under is set at 221. (see up-to-date odds for every game this week on our NBA odds page). Tip-off is set for 8:30 p.m. ET.

Before making any Lakers vs. Spurs picks, you NEED to check out the NBA predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned almost $9,000 in profit on its top-rated NBA picks over the past three-plus seasons. The model finished up almost $600 on its top-rated picks last season and entered Week 2 of the 2021-22 NBA season on a stunning 103-68 roll on top-rated NBA picks against the spread. Anyone following it has seen HUGE returns!  

The model knows the Lakers have struggled on defense. Los Angeles has given up at least 115 points in every game this season. The Lakers have the NBA's fifth-worst defensive rating ahead of Tuesday night. The visitors will have to be more locked in defensively to secure a convincing win.

The model also knows the Spurs have been efficient on offense. While San Antonio is 1-2, it boasts the league's eighth-ranked offensive rating (109.6). The Spurs have a middle-of-the-pack scoring defense are averaging 117 points per game at home. 

Now, it has set its sights on Lakers vs. Spurs. We can tell you the model is leaning under the total, and it also says one side of the spread hits in well over 60 percent of simulations! You ABSOLUTELY need to see it before locking in any NBA picks.

Who wins Lakers vs. Spurs? And which side of the spread hits in well over 60 percent of simulations? ... Join SportsLine right now to find out which side of the Lakers vs. Spurs spread you should be all over Tuesday, all from the model on a roll on NBA picks!