Lakers vs. Celtics prediction, odds, line: Proven model reveals 2026 NBA picks for Sunday, February 22

The NBA's preeminent rivalry will be renewed on Sunday Night Basketball as the Boston Celtics visit the Los Angeles Lakers. Boston (36-19) has won eight of its last 10, including a Thursday victory over Golden State. L.A. (34-21) is coming off back-to-back victories, most recently a Friday triumph over the Clippers. The Celtics have won the last two matchups, including a 126-105 victory on Dec. 5.

Tipoff is at 6:30 p.m. ET from Crypto.com Arena in Los Angeles. The latest Celtics vs. Lakers odds list Boston as the 1.5-point favorite, with the over/under at 228.5.

Before making any Lakers vs. Celtics picks, you NEED to see what the SportsLine Projection Model has to say.

SportsLine's model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model exited the NBA All-Star break on a sizzling 38-17 roll on top-rated NBA spread picks dating back to last season. Anyone following could have seen HUGE returns!

The model has simulated Celtics vs. Lakers 10,000 times and the results are in. The model is going Over on the point total in an A-rated pick, and it also says one side of the spread hits almost 70% of the time!

Who wins Lakers vs. Celtics, and which side of the spread hits almost 70% of the time? ... Join SportsLine right now to find out which side of the Celtics vs. Lakers spread you should be all over, all from the model on a 38-17 roll on top-rated NBA spread picks!