The No. 4 Kentucky Wildcats will take on the Duquesne Dukes at 7 p.m. ET on Friday at Rupp Arena. The Wildcats rolled to a 95-63 win over Howard in their season opener, but they will likely be without their best player again in this game. They are favored by 19 points in the latest Kentucky vs. Duquesne odds from Caesars Sportsbook, while the over/under is set at 147. 

Before you make any Duquesne vs. Kentucky picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past six years, the proprietary computer model has generated an impressive profit of more than $1,200 for $100 players on its top-rated college basketball picks against the spread. Anybody who has followed it has seen profitable returns.

Now, it has simulated Kentucky vs. Duquesne 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in over 50% of simulations. You absolutely need to see it before locking in your own picks.

So who wins Kentucky vs. Duquesne? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks... If you're already a member, see the picks below!