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Kansas vs. Duke odds, line, spread: Proven model reveals college football picks, predictions for Week 4, 2022

The SportsLine Projection Model has simulated Duke vs. Kansas 10,000 times
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The Kansas Jayhawks will take on the Duke Blue Devils at noon ET on Saturday at Kivisto Field at David Booth Kansas Memorial Stadium. The Jayhawks and Blue Devils rarely meet on the gridiron in a significant game, but that will be the case on Saturday when the pair of unbeaten teams collide. Kansas is favored by 7 points in the latest Kansas vs. Duke odds from Caesars Sportsbook, while the over/under is set at 65. 

Before you make any Duke vs. Kansas picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,300 for $100 players on its top-rated college football picks against the spread. It enters Week 4 of the 2022 college football season on a 51-43 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

Now, it has simulated Kansas vs. Duke 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in nearly 60% of simulations. You absolutely need to see it before locking in your own picks.

So who wins Kansas vs. Duke? And which side of the spread hits nearly 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.

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SportsLine Staff