Kansas vs. Cincinnati odds, prediction: 2026 men's college basketball picks for Feb. 21 from proven model

The eighth-ranked Kansas Jayhawks look to stay on track for a premium NCAA Tournament seed when they host the Cincinnati Bearcats Saturday on CBS and Paramount+ (sign up here). Kansas is 20-6 (10-3 Big 12), while Cincinnati is 14-12 (6-7 Big 12) this season.

Tipoff from Allen Fieldhouse is set for 1 p.m. ET. The Jayhawks are 10.5-point favorites in the latest Cincinnati vs. Kansas odds, while the over/under is 138.5. 

Before making any Kansas vs. Cincinnati picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times and it entered Week 16 on a sizzling 11-1 run on its top-rated over/under college basketball picks dating back to last season, and is on a 13-7 run on top-rated CBB side picks. Anyone following its college basketball betting advice at sportsbooks and on betting apps could have seen strong returns.

The model has simulated this matchup 10,000 times and the results are in. The model is going Over, and it also says one side of the spread hits more than 50% of the time!

So who wins Cincinnati vs. Kansas, and which side of the spread hits more than 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!