A Big 12 battle is on tap between the No. 12 Iowa State Cyclones and the No. 5 Kansas State Wildcats at 9 p.m. ET on Tuesday at James H. Hilton Coliseum. Kansas State is coming off consecutive wins over then-No. 2 Kansas and Texas Tech to jump to the top of the conference standings. The Cyclones are favored by 6 points in the latest Iowa State vs. Kansas State odds from Caesars Sportsbook, while the over/under is set at 134.5. 

Before you make any Kansas State vs. Iowa State picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. The model enters Week 12 of the season 45-26 on all-top rated college basketball picks, returning more than $1,100 for $100 players. Anybody who has followed it has seen huge returns.

Now, it has simulated Iowa State vs. Kansas State 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in over 50% of simulations. You absolutely need to see it before locking in your own picks.

So who wins Iowa State vs. Kansas State? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks... If you're already a member, see the picks below!