Illinois vs. UTSA odds, line, spread: Proven model reveals college football picks, predictions for Week 1, 2021

The Illinois Fighting Illini will take on the UTSA Roadrunners at 7:30 p.m. ET next Saturday at Memorial Stadium. The Fighting Illini are favored by five points in the latest Illinois vs. UTSA odds from Caesars Sportsbook, and the over-under is set at 50. Before you make any UTSA vs. Illinois picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of over $3,600 for $100 players on its top-rated college football picks against the spread. It also enters Week 1 of the 2021 season on a 57-37 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, it has simulated Illinois vs. UTSA 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in nearly 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Illinois vs. UTSA? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks...If you're already a member, see the picks below!