Florida vs. Missouri odds, line, spread: Proven model reveals college football picks, predictions for Week 6, 2022

An SEC battle is on tap between the Florida Gators and the Missouri Tigers at noon ET on Saturday at Florida Field at Ben Hill Griffin Stadium. Florida is trying to avoid its third straight conference loss after falling to Kentucky and Tennessee in its first two SEC games. The Gators are favored by 11 points in the latest Florida vs. Missouri odds from Caesars Sportsbook, while the over/under is set at 55. 

Before making any Missouri vs. Florida picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Florida vs. Missouri 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits more than 50% of the time. You absolutely need to see it before locking in your own picks.

So who wins Florida vs. Missouri? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.