The Atlanta Falcons will take on the San Francisco 49ers at 1 p.m. ET on Sunday at Mercedes-Benz Stadium. The Falcons had their two-game winning streak snapped in a 21-15 loss at Tampa Bay last week. San Francisco is favored by 4 points in the latest Falcons vs. 49ers odds from Caesars Sportsbook, while the over/under is set at 45.5. 

Before you make any 49ers vs. Falcons picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 6 of the 2022 NFL season on an incredible 146-106 run on top-rated NFL picks that dates back to the 2017 season. The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, it has simulated Falcons vs. 49ers 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in almost 60% of simulations. You absolutely need to see it before locking in your own picks.

So who wins Falcons vs. 49ers? And which side of the spread hits almost 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks.