The No. 2-seed Villanova Wildcats take on the No. 15-seed Delaware Blue Hens on Friday in a 2022 NCAA Tournament first-round matchup. Tipoff is set for 2:45 p.m. ET in the South Region showdown and the game will be televised on CBS.

The Wildcats are 15-point favorites and the over-under for total points scored is 135.5 in the latest Caesars Sportsbook college basketball odds for Delaware vs. Villanova in the NCAA Tournament. (See up-to-date odds for every game this week on our college basketball odds page.)

Before making any Delaware vs. Villanova  picks or any other 2022 NCAA Tournament predictions, be sure to check out what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $1,500 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns

Now, the model has set its sights on the NCAA Tournament and Delaware vs. Villanova  on Friday. We can tell you it is leaning over the total, predicting at least 144 combined points, and it also says one side of the spread covers in nearly 60 percent of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Delaware vs. Villanova? And which side of the spread covers in nearly 60 percent of simulations? ... Join SportsLine right now to find out which side of the Villanova vs. Delaware spread you should be all over Thursday, all from the model on a roll on college basketball picks!