Creighton vs. Connecticut odds, line, spread: Proven model reveals college basketball picks, predictions for Mar 2, 2022

Creighton freshman guard Ryan Nembhard was one of four players to average double-digit points this season for the Bluejays, but after a season-ending wrist injury against St. John's on Feb. 23, he won't be on the court against No. 18 Connecticut on Wednesday at 8:30 p.m. ET. Creighton beat UConn earlier this season, 59-55, but Nembhard had just six points in the win. The Bluejays, who are 10-3 at home this season hope they can make do without him against a Huskies side that is just 5-4 on the road this year.

The Huskies are favored by four points in the latest Creighton vs. Connecticut odds from Caesars Sportsbook, and the over-under is set at 135. Before you make any Connecticut vs. Creighton picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $1,700 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Creighton vs. Connecticut 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in over 60 percent of simulations. You absolutely need to see it before locking in your own picks.

Who wins Creighton vs. Connecticut? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks ... If you're already a member, see the picks below!