The Indianapolis Colts will try to hand the New England Patriots their first international loss when the teams meet at Frankfurt Stadium in Germany on Sunday. Indianapolis (4-5) is coming off a 27-13 victory at Carolina, but has lost nine of its last 10 meetings with New England, including a pair of playoff matchups. The Patriots (2-7) got off to their worst nine-game start since 2000, but are 3-0 in international games, with two wins coming in London and the other in Mexico City. Colts vs. Patriots is the final NFL international game this season.

Kickoff is set for 9:30 a.m. ET. Indianapolis is a 2-point favorite in the latest Colts vs. Patriots odds, while the over/under for total points scored is 43. Before making any Patriots vs. Colts picks of your own, you NEED to check out the NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model entered Week 10 of the 2023 NFL season on an incredible 174-123 run on top-rated NFL picks that dates back to the 2017 season. It also is on a 28-15 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP.

The model knows Indianapolis ended its three-game losing streak last week by capitalizing on turnovers. Cornerback Kenny Moore II made two interceptions and returned them both for touchdowns, becoming the first player to accomplish the feat since Tampa Bay safety Mike Edwards in Week 2 of the 2021 season. Zach Moss leads the Colts in rushing with a career-high 615 yards, while Jonathan Taylor recorded 69 scrimmage yards and made his first TD catch since Week 17 of the 2021 campaign in last week's victory.

The model also is aware that New England squandered a fourth-quarter lead against Washington in Week 9 en route to its fifth loss in six games, a 20-17 setback at home. The Patriots received a solid performance from running back Rhamondre Stevenson, who rushed for a season-high 87 yards and a touchdown while making four catches for 42 yards. The 25-year-old gained 60 yards on the ground and hauled in a TD pass in New England's 26-3 home win over Indianapolis last season. 

Now, it has set its sights on Colts vs. Patriots. We can tell you the model is leaning Over the total, and it also says one side of the spread cashes in well over 50% of simulations! You ABSOLUTELY need to see it before locking in any NFL picks.

Who wins Colts vs. Patriots in Germany? And which side of the spread cashes well over 50% of the time? ... Join SportsLine right now to find out which side of the Patriots vs. Colts spread you should be all over Sunday, all from the model on a 174-123 roll on NFL picks!