A Pac-12 battle is on tap between the Colorado Buffaloes and the No. 16 Southern California Trojans at 7:30 p.m. ET on Thursday at the CU Events Center. Colorado is 12-4 overall and 9-1 at home, while the Trojans are 14-2 overall and 4-1 on the road. Both teams are currently sitting in a tie for third place in the conference standings. 

The Trojans are favored by 2 points in the latest Colorado vs. Southern California odds from Caesars Sportsbook, while the over-under is set at 137. Before you make any Southern California vs. Colorado picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $2,400 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Colorado vs. Southern California 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Colorado vs. Southern California? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.