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The Week 5 college football schedule is highlighted by three ranked matchups as Alabama (-6) takes on Mississippi State, Florida (-4.5) plays Missouri and Ohio State (-14) travels to take on Iowa in the CBS and Paramount+ game. Claim the latest Polymarket promo code SPORTSLINE to get a $25 trading bonus after a $10 deposit:
Before making any college football picks for Week 5 on those games or others, be sure to check out the college football picks and parlay from proven CFB expert Thomas Casale.
A frequent guest on national radio and TV shows to discuss college sports, Casale has been betting -- and winning -- for more than 30 years. He's coming off a 3-0 sweep last week and is now 5-1 on picks in this column over the past two weeks!
Now, he's turned his attention to the latest college football odds (see the latest college football lines for each game this week on our college football odds page) and is revealing his top plays. A parlay of them would return around +600.
For this week, Casale is going Over 59.5 points in Mississippi State vs. Alabama. "This should be a fun, exciting game between two top-25 offenses," Casale said. "Keelon Russell and Kamario Taylor are emerging stars, and I expect both quarterbacks to shine on Saturday in what could be a shootout in Starkville."
Casale has found two more college football picks he loves, including backing a favorite that is "a bad matchup" on paper for its opponent! You ABSOLUTELY need to see what he's playing before locking in any college football picks.
What are Casale's best bets for Week 5, and which favorite rolls to a big win? ... Join SportsLine right now to see Thomas Casale's best bets, all from one of the top college football handicappers in the nation!
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