The Kansas City Chiefs and Arizona Cardinals will square off in preseason action on Friday. Kickoff in Glendale is set for 8 p.m. ET. The Chiefs are favored by three points in the latest Chiefs vs. Cardinals odds from Caesars Sportsbook, while the over-under is 41.

Before you make any Chiefs vs. Cardinals picks or any other NFL predictions, you NEED to see which side SportsLine NFL expert is on. 

The SportsLine senior analyst and Early Edge podcast regular enters the 2021 season 351-291 all-time on NFL sides (plus $2,212), including a 326-280 ATS mark. In addition, Hartstein has an amazing 16-4 record on his last 20 picks involving Kansas City, returning more than $1,100. Anyone who has followed him is way up.

Now, Hartstein has locked in another confident against the spread pick for Chiefs vs. Cardinals. We can tell you he's leaning under the total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

Who wins Chiefs vs. Cardinals? And what critical X-factor makes one side of the spread a must-back? ... Join SportsLine right now to see which side of the Chiefs vs. Cardinals spread to jump on, all from the expert who's an outstanding 16-4 on Chiefs picks!