The Philadelphia 76ers welcome the Boston Celtics to town for a high-profile Eastern Conference matchup at 7:30 p.m. ET on Tuesday. Boston is favored by two points at Caesars Sportsbook, while the Over-Under is set at 210 (see up-to-date odds for every game this week on our NBA odds page). 

Before making any Celtics vs. 76ers picks, you NEED to check out the NBA predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past three-plus seasons. The model enters Week 17 of the 2021-22 NBA season on a stunning 67-39 roll on all top-rated NBA picks, returning over $2,200. Anyone following it has seen HUGE returns.

The model knows the Celtics are No. 4 in the NBA in net rating, out-scoring opponents by almost five points per 100 possessions. Boston's defense is the biggest reason for its success, as opponents are scoring only 1.05 points per possession against the Celtics this season and 1.01 points per possession since Jan. 1. The Celtics are in the top two of the NBA in field-goal percentage allowed, 2-point percentage allowed and assists allowed this season. Boston is also giving up only 41.9 points in the paint per game, and Philadelphia is last in the league in offensive rebound rate this season.

The model also knows the Sixers are No. 2 in the NBA in turnovers, committing fewer than 13 per game. That allows Philadelphia to boost offensive efficiency, and the team's defense is potent. Philadelphia is holding opponents to 108.4 points per 100 possessions, a top-eight mark in the NBA, and the 76ers are in the top 10 in field-goal percentage allowed and 3-point percentage allowed. Opponents are attempting 20.6 free-throw attempts per game against the 76ers, and Philadelphia is in the top eight of the league in assists allowed and blocked shots.

Now, it has set its sights on Celtics vs. 76ers. We can tell you the model is leaning under the total, and it also says one side of the spread hits in almost 60 percent of simulations! You ABSOLUTELY need to see it before locking in any NBA picks.

Who wins Celtics vs. 76ers? And which side of the spread hits in almost 60 percent of simulations? ... Join SportsLine right now to find out which side of the Celtics vs. 76ers spread you should be all over Tuesday, all from the model on a roll on NBA picks!