The Chicago White Sox go for the interleague series sweep when they meet the St. Louis Cardinals on Wednesday afternoon. First pitch is at 2:10 p.m. ET at Guaranteed Rate Field in Chicago. William Hill Sportsbook lists Chicago as the -203 favorite (risk $203 to win $100) in the latest Cardinals vs. White Sox odds. The Over-Under for total runs is set at 8.5 (see the latest lines for every game on our MLB odds page) in this matchup.

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