Broncos vs. Chiefs prediction, line, odds: Proven model releases spread pick for 2026 NFL Week 1 matchup on Monday Night Football

The Kansas City Chiefs look to rebound from a rare non-playoff year when they kick off the 2026 season against the defending AFC West champion Denver Broncos on Monday Night Football. After winning the AFC West for nine consecutive seasons and reaching the Super Bowl in five of six seasons, Kansas City slumped to 6-11 in 2025. Denver, meanwhile, was 14-3 last season and earned its first division title since 2015. The Broncos reached the AFC Championship Game where they dropped a 10-7 decision to the New England Patriots.

Kickoff is at 8:15 p.m. ET from Arrowhead Stadium in Kansas City, Mo. The latest Broncos vs. Chiefs odds have Kansas City as 2.5-point favorites, while the over/under for total points scored is 42.5 via SportsLine consensus.

Before making any Broncos vs. Chiefs picks, or 2026 NFL Week 1 predictions of your own, you NEED to see which side the proven SportsLine projection model is on.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters the 2026 NFL season on a 53-37 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!

Now, the model has locked in another confident pick for Broncos vs. Chiefs on Monday, Sept. 14.

We can tell you it's leaning Under the point total, but also says that one side of the spread hits over 50% of the time! You ABSOLUTELY NEED to see which side to back before locking in any picks of your own.

So who wins Broncos vs. Chiefs in NFL Week 1, and which side of the spread hits in over 50% of simulations? ... Join SportsLine RIGHT NOW to see which side of the Broncos vs. Chiefs line to back, all from the model that has gone 53-37 on top-rated picks since 2024!

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