The Denver Broncos will close Week 6 of the 2022 NFL season with a division battle at 8:15 p.m. ET on Monday Night Football. Los Angeles is favored by 4.5 points at Caesars Sportsbook, while the over/under is 45.5. Before making any Broncos vs. Chargers picks, you NEED to check out the NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 6 of the 2022 NFL season on an incredible 146-106 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP.

The model knows the Broncos are allowing only 16.0 points per game and 1.30 points per drive this season. Both metrics rank in the top five, and Denver is also in the top five in total yards allowed per game and per drive. Denver leads the league in passing defense, giving up only 176.6 yards per game, and sits atop the NFL in red zone efficiency allowed at 27.3% this season.

The model also knows the Chargers are dynamic on offense. Justin Herbert is one of the game's best quarterbacks, and Los Angeles is averaging 390.4 total yards per game, a top-five mark. The Chargers are producing 24.4 points per game and 2.44 points per possession, committing only four turnovers this season. Los Angeles has the best sack rate allowed (2.4%) in the league.

Now, it has set its sights on Broncos vs. Chargers. We can tell you the model is leaning Over the total, and it also says one side of the spread has ALL the value! You ABSOLUTELY need to see it before locking in any NFL picks.

Who wins Broncos vs. Chargers on Monday Night Football? And which side of the spread has ALL the value? ... Join SportsLine right now to find out which side of the Broncos vs. Chargers spread you should be all over, all from the model on a 146-106 roll on NFL picks!