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Brewers vs. Padres odds, lines: Advanced computer model reveals picks for Tuesday's MLB matchup

SportsLine's Projection Model has generated picks for Tuesday's game between Milwaukee and San Diego

By@SportsLineUpdated: May 24, 2022 3:58PM UTC . 3 min read

The San Diego Padres attempt to extend their winning streak to six games when they host the Milwaukee Brewers on Tuesday for the middle contest of their three-game series. San Diego (28-14), which trails the National League West-leading Los Angeles Dodgers by one-half game, needed 10 innings to record a 3-2 victory in Monday's series opener. The loss was the second straight for Milwaukee (26-16), which leads St. Louis by two games in the NL Central. First pitch in this MLB on TBS matchup at Petco Park is set for 9:40 p.m. ET.

Milwaukee is listed as a -135 favorite (risk $135 to win $100) on the money line in the latest Brewers vs. Padres odds from Caesars Sportsbook, while the over-under for total runs scored is 6.5 (see the latest lines for every game on our MLB odds page).

Before making any Padres vs. Brewers picks, you NEED to see the latest MLB predictions from the SportsLine Projection Model.

The model simulates every MLB game 10,000 times and is off to a strong start to the 2022 season. It's on a 41-30 roll on top-rated MLB money-line picks through seven weeks, returning almost $600 for $100 players. Anyone following it has seen HUGE returns!

The model knows San Diego boasts the major leagues' leading hitter in Manny Machado, who owns a .365 batting average despite going 0-for-4 on Monday. The five-time All-Star entered the series with a six-game hitting streak during which he went 12-for-27 with three multi-hit performances. The Padres' rotation has been one of the best of 2022 thus far, having produced a league-leading 22 quality starts.

The model also knows Milwaukee won five of six before dropping back-to-back games. The Brewers' pitching staff also has been strong this season as it is tied for second in the majors with 19 quality starts and leads all teams with 423 strikeouts. Hunter Renfroe, Willy Adames, and Rowdy Tellez have belted nine home runs apiece for Milwaukee, which ranks first in the NL with 55 blasts.

Now, it has set its sights on Brewers vs. Padres. We can tell you the model is projecting 6.8 total runs, and it also says one side of the money line has all the value! You ABSOLUTELY need to see it before locking in any MLB picks of your own.

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