Athletics vs. Yankees odds, line, prediction: 2026 MLB picks for Thursday afternoon from proven model

The Athletics look to even the series as they battle the New York Yankees in the second game of the series on Thursday afternoon. New York is coming off a 5-3 win over the Athletics on Tuesday. The Athletics (4-7), who have lost their last two on the road, are 2-6 on the road this season. The Yankees (8-3), who have won two of their last three at home, are 3-2 on their home field in 2026.

First pitch from Yankee Stadium in New York is set for 1:35 p.m. ET. The New York Yankees have a 1155-785 all-time series lead over the Athletics, and have won seven of the last 10 meetings. New York is a -213 favorite on the money line (risk $213 to win $100) in the latest Athletics vs. Yankees odds, while the over/under, is 8. Before making any Yankees vs. Athletics picks, or MLB predictions, you NEED to see what the SportsLine Projection Model has to say.

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The model has simulated Athletics vs. Yankees 10,000 times and the results are in. The model is going Over on the total, and is also says one side of the money line has ALL the value!

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