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NFC contenders face off in a marquee NFL Week 5 showdown, as Sam Darnold and the Seattle Seahawks host Brock Purdy and the San Francisco 49ers. The Seahawks (3-1) have scored 30-plus points three weeks in a row while allowing the fewest yards in the NFL. The 49ers (4-0) have yet to lose at all, with three of those victories by 10 points or more. Only the Bills have scored more points through four weeks than the Niners. Claim the latest Polymarket promo code SPORTSLINE to get a $50 trading bonus after a $10 deposit:
Kickoff is set for 4:25 p.m. ET from Lumen Field in Seattle. The latest 49ers vs. Seahawks odds have Seattle as a 3-point favorite. The over/under for total points scored is 47.
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