The PGA Tour heads to Greensboro, NC this week for the 2022 Wyndham Championship. The tournament is the last on the PGA Tour schedule before the FedEx Cup Playoffs begin next week and tees off Thursday at Sedgefield Country Club. Will Zalatoris and Shane Lowry are co-favorites this week at 16-1 in the latest Wyndham Championship odds from Caesars Sportsbook. Other top contenders in the Wyndham Championship field include Webb Simpson (18-1), Billy Horschel (20-1), Sungjae Im (20-1), Corey Conners (25-1), and Russell Henley (28-1). The total Wyndham Championship purse is $7.3 million, with $1.314 million going to the winner, making it imperative that you nail your One and Done picks this week. 

Before locking in your own 2022 Wyndham Championship One and Done picks, you NEED to see what daily Fantasy sports pro Mike McClure has to say.

The One and Done format is growing in popularity. It has several noticeable similarities to NFL Survivor pools, with the main difference being entries are not eliminated with a bad week. Players pick one golfer per week and earn points based on their selected golfer's prize money for that tournament. Golfers can only be used once per season, and the point format makes nailing majors and big money tournaments critical.

McClure is a DFS legend with over $2 million in career winnings, and he's been RED-HOT on his PGA picks dating back to the PGA Tour restart in June of 2020. McClure uses his proprietary simulation model to analyze the field and crush his golf picks. In fact, the model is up over $9,600 on its best bets since the restart, nailing tournament after tournament.

McClure's model included J.T. Poston in its best bets to win the 2022 John Deere Classic. That bet hit at +5500, and for the entire tournament, McClure's best bets returned almost $1,100. At the 2022 Masters, McClure's model was all over Scottie Scheffler's first career major championship victory heading into the weekend.

In addition, McClure's best bets included Collin Morikawa winning outright at the 2021 Open Championship, even though he was listed as a massive 40-1 long shot. The model was also all over Jon Rahm's (10-1) first career major championship victory at the 2021 U.S. Open. Rahm was two strokes off the lead heading into the weekend, but the model still projected him as the winner.

This same model has also nailed a whopping eight majors entering the weekend! Anyone who has followed it has seen MASSIVE returns!

McClure has been nailing his one and done PGA picks all year. He nailed Hideki Matsuyama's outright win at the Sony Open, then followed that up by picking Will Zalatoris at the Farmers Insurance Open. The result: Zalatoris finished in sole possession of second place, taking home $915,600. At the Waste Management Phoenix Open McClure's top two One and Done picks were Xander Schauffele and Brooks Koepka, who both finished T-3, which was good for $434,600 each. Then at the Mexico Open, McClure's top two picks, Jon Rahm and Tony Finau, finished in first and second place, respectively.

Now, McClure has set his sights on the 2022 Wyndham Championship and just revealed his optimal One and Done picks. They are a must-see for any player looking for an edge in their One and Done pool.

We can tell you that one of McClure's favorite Wyndham Championship Open One and Done picks is Corey Conners, who is currently listed at 25-1 to win the tournament at Caesars. Conners, who is currently the No. 31 player in the world, has seven top-15 finishes in 2022, including sixth place at the Masters, and is easily one of the most talented players in the field this week.

McClure is also targeting another One and Done sleeper who's listed at 28-1 in the 2022 Wyndham Championship odds and is primed to blow up this week, giving you a HUGE return! Picks like these could be the difference between winning your One and Done pool or going home with nothing. You ABSOLUTELY need to see who it is before locking in your pick.

So what are the top One and Done picks for the 2022 Wyndham Championship? And which under-the-radar golfers offer HUGE One and Done value? ... Join SportsLine here to see the top 2022 Wyndham Championship One and Done picks, all from the expert who's made nearly $2 million in daily Fantasy sports!