2022 U.S. Open women's odds, picks: Swiatek vs. Pegula quarterfinals best bets and predictions from proven expert

World No. 1 Iga Swiatek continues the pursuit for her second Grand Slam title of the year when she faces Jessica Pegula in the women's quarterfinals of the 2022 U.S. Open at the Billie Jean King National Tennis Center in Flushing Meadows on Wednesday. The top-seeded Swiatek won the French Open for the second time in her career back in June, defeating Pegula in straight sets in the quarters along the way. Pegula, the No. 8 seed, has yet to win a major tournament but also reached the quarterfinals of the Australian Open earlier this year.

First serve is scheduled for 7 p.m. ET. Swiatek is the -230 favorite (risk $230 to win $100) in the latest Swiatek vs. Pegula odds from Caesars Sportsbook while Pegula is a +175 underdog. The over/under for total games in the match is 21.5, with Swiatek favored by 3.5 games. Before you make any Pegula vs. Swiatek picks or 2022 U.S. Open predictions, you NEED to see what tennis expert Jose Onorato has to say.

Onorato grew up playing competitive tennis in Caracas, Venezuela. After coming to the U.S., he trained with famed coach Nick Bollettieri at IMG Academy in Florida and faced players like Robert Farah, now one of the world's top-ranked doubles players.

Onorato, who holds dual degrees in finance and economics from the University of Miami, does extensive research before placing any tennis bet. He studies current form, players' tendencies on a particular surface, weather conditions and many other relevant factors. That systematic approach helped Onorato go 69-46 -- up 54.98 units -- from January through July.

The expert knows Swiatek followed her win at Roland Garros with a third-round exit at Wimbledon but has bounced back nicely in this tournament. After posting straight-set victories in the first three rounds, the 21-year-old Pole rallied to defeat Jule Niemeier 2-6, 6-4, 6-0 in the round of 16. Swiatek lost her first career meeting with Pegula before defeating the 28-year-old American twice already this year -- 6-2, 7-5 in the semifinals of Miami Open and 6-3, 6-2 in the quarters of the French Open. Pegula has recorded three straight-set triumphs in this tournament thus far, including a 6-3, 6-2 victory against No. 21 seed Petra Kvitova in the fourth round.

Now, Onorato has scrutinized the Swiatek vs. Pegula matchup in the women's quarterfinals of the 2022 U.S. Open and released his coveted picks. You ABSOLUTELY need to see what it is before locking in any 2022 U.S. Open picks of your own!

Who wins the Swiatek vs. Pegula women's quarterfinal match at the 2022 U.S. Open? ... Join SportsLine right now to see Jose Onorato's prediction and analysis for the 2022 U.S. Open women's quarterfinal match, all from the tennis expert who went 69-46 from January through July!