NFL schedule 2021: Week 4 picks, odds, predictions, best bets, spreads, lines, TV coverage for all 16 games
The first three weeks of the 2021 NFL season have lived up to the lofty expectations that have become the norm for the National Football League. In Week 3, Justin Tucker nailed a NFL record 66-yard, walk off field goal to give the Ravens a win over the Lions; Justin Herbert out-dueled Patrick Mahomes, leading the Chargers to a 30-24 win over the Chiefs; Matthew Stafford and the Rams cemented their place among the top Super Bowl 56 contenders with a dominating 34-24 win over Tom Brady and the Buccaneers; and Aaron Rodgers delivered a clutch fourth quarter performance, guiding the Packers to a 30-28 win over the 49ers.Â
Against the spread underdogs 9-7 in Week 3, continuing the trend of betting favorites falling short. Will that trend continue in Week 4? Or will this week tilt more towards the betting favorites? Â Â
Who wins every NFL game? And which teams will sink your bankroll? Join SportsLine now to get NFL picks every week, all from the model that simulates every game 10,000 times and is up almost $8,000.Â
The NFL Week 4 schedule features a full slate of games with several intriguing matchups including Cowboys vs. Panthers in a matchup between two of the top teams in the NFC thus far; the Rams vs. Cardinals, in a matchup between two undefeated teams with Super Bowl aspirations and MVP candidates at quarterback; Seahawks vs. 49ers in a matchup between two bitter NFC West rivals; and Buccaneers vs. Patriots on Sunday Night Football, where fans Tom Brady will make his return to Gillette Stadium where he will likely break the NFL career passing yards record early in the first half.Â
Here is a full rundown of the NFL Week 4 slate of games and TV schedule, as well as odds, picks, and predictions for several matchups.Â
Which Fantasy Football sleepers, breakouts and busts should you target and fade? And which QB shocks the NFL with a top-five performance? Join SportsLine now to get 2021 Fantasy Football cheat sheets for every single position, all from the model that called Josh Allen's huge season.
Jacksonville Jaguars vs. Cincinnati Bengals
- Bengals vs. Jaguars date and time: Thursday, September 30 at 8:20 p.m. ET
- Bengals vs. Jaguars spread: Bengals -7.5
- Bengals vs. Jaguars over-under: 46
- Bengals vs. Jaguars moneyline: Jaguars +280, Bengals -350
- Bengals vs. Jaguars TV Coverage: NFL Network
Expert Bengals vs. Jaguars picks HERE.
Washington Football Team vs. Atlanta Falcons
- Falcons vs. Washington date and time: Sunday, October 3 at 1 p.m. ET
- Falcons vs. Washington spread: Washington -1.5
- Falcons vs. Washington over-under: 48
- Falcons vs. Washington moneyline: Washington -120, Falcons +100
- Falcons vs. Washington TV coverage: Fox
Houston Texans vs. Buffalo Bills
- Texans vs. Bills date and time: Sunday, October 3 at 1 p.m. ET
- Texans vs. Bills spread: Bills -16.5
- Texans vs. Bills over-under: 47
- Texans vs. Bills moneyline: Bills -1600, Texans +850
- Texans vs. Bills TV coverage: CBS
Detroit Lions vs. Chicago Bears
- Lions vs. Bears date and time: Sunday, September 19 at 1 p.m. ET
- Lions vs. Bears spread: Bears -3
- Lions vs. Bears over-under: 42.5
- Lions vs. Bears moneyline: Bears -150, Lions +130
- Lions vs. Bears TV coverage: Fox
Who wins every NFL game? And which teams will sink your bankroll? Join SportsLine now to get NFL picks every week, all from the model that simulates every game 10,000 times and is up almost $8,000.
Carolina Panthers vs. Dallas Cowboys
- Panthers vs. Cowboys date and time: Sunday, October 3 at 1 p.m. ET
- Panthers vs. Cowboys spread: Cowboys -5
- Panthers vs. Cowboys over-under: 50.5
- Panthers vs. Cowboys moneyline: Panthers +180, Cowboys -220
- Panthers vs. Cowboys TV coverage: Fox
Expert Cowboys vs. Panthers prop bet picks HERE.
Indianapolis Colts vs. Miami Dolphins
- Colts vs. Dolphins date and time: Sunday, October 3 at 1 p.m. ET
- Colts vs. Dolphins spread: Dolphins -1.5
- Colts vs. Dolphins over-under: 43
- Colts vs. Dolphins moneyline: Dolphins -130, Colts +110
- Colts vs. Dolphins TV coverage: CBS
Cleveland Browns vs. Minnesota Vikings
- Browns vs. Vikings date and time: Sunday, October 3 at 1 p.m. ET
- Browns vs. Vikings spread: Browns -2
- Browns vs. Vikings over-under: 51.5
- Browns vs. Vikings moneyline: Browns -130, Vikings +110
- Browns vs. Vikings TV coverage: CBS
New York Giants vs. New Orleans Saints
- Giants vs. Saints date and time: Sunday, October 3 at 1 p.m. ET
- Giants vs. Saints spread: Saints -8
- Giants vs. Saints over-under: 43
- Giants vs. Saints moneyline: Saints -400, Giants +310
- Giants vs. Saints TV coverage: Fox
Which Fantasy Football sleepers, breakouts and busts should you target and fade? And which QB shocks the NFL with a top-five performance? Join SportsLine now to get 2021 Fantasy Football cheat sheets for every single position, all from the model that called Josh Allen's huge season.
Tennessee Titans vs. New York Jets
- Titans vs. Jets date and time: Sunday, October 3 at 1 p.m. ET
- Titans vs. Jets spread: Titans -7.5
- Titans vs. Jets over-under: 46
- Titans vs. Jets moneyline: Titans -380, Jets +300
- Titans vs. Jets TV coverage: CBS
Expert Jets vs. Titans picks HERE.
Kansas City Chiefs vs. Philadelphia Eagles
- Chiefs vs. Eagles date and time: Sunday, October 3 at 1 p.m. ET
- Chiefs vs. Eagles spread: Chiefs -7
- Chiefs vs. Eagles over-under: 54.5
- Chiefs vs. Eagles moneyline: Eagles +270, Chiefs -340
- Chiefs vs. Eagles TV coverage: CBS
Expert Eagles vs. Chiefs prop bet picks HERE.
Arizona Cardinals vs. Los Angeles Rams
- Rams vs. Cardinals date and time: Sunday, September 19 at 4:05 p.m. ET
- Rams vs. Cardinals spread: Rams -4.5
- Rams vs. Cardinals over-under: 54.5
- Rams vs. Cardinals moneyline: Cardinals +190, Rams -230
- Rams vs. Cardinals TV coverage: Fox
Seattle Seahawks vs. San Francisco 49ers
- Seahawks vs. 49ers date and time: Sunday, October 3 at 4:25 p.m. ET
- Seahawks vs. 49ers spread: 49ers -2.5
- Seahawks vs. 49ers over-under: 52
- Seahawks vs. 49ers moneyline: Seahawks +140, 49ers -160
- Seahawks vs. 49ers TV coverage: Fox
Expert 49ers vs. Seahawks picks HERE.
Who wins every NFL game? And which teams will sink your bankroll? Join SportsLine now to get NFL picks every week, all from the model that simulates every game 10,000 times and is up almost $8,000.
Baltimore Ravens vs. Denver Broncos
- Broncos vs. Ravens date and time: Sunday, October 3 at 4:25 p.m. ET
- Broncos vs. Ravens spread: Broncos -1
- Broncos vs. Ravens over-under: 44
- Broncos vs. Ravens moneyline: Ravens -105, Broncos -115
- Broncos vs. Ravens TV coverage: CBS
Expert Ravens vs. Broncos prop bet picks HERE.
Pittsburgh Steelers vs. Green Bay Packers
- Steelers vs. Packers date and time: Sunday, October 3 at 4:25 p.m. ET
- Steelers vs. Packers spread: Packers -6.5
- Steelers vs. Packers over-under: 45.5
- Steelers vs. Packers moneyline: Packers -320, Steelers +250
- Steelers vs. Packers TV coverage: Fox
Tampa Bay Buccaneers vs. New England Patriots
- Buccaneers vs. Patriots date and time: Sunday, October 3 at 8:20 p.m. ET
- Buccaneers vs. Patriots spread: Buccaneers -6.5
- Buccaneers vs. Patriots over-under: 49
- Buccaneers vs. Patriots moneyline: Patriots +240, Buccaneers -300
- Buccaneers vs. Patriots TV coverage: NBC
Las Vegas Raiders vs. Los Angeles Chargers
- Lions vs. Packers date and time: Monday, October 4 at 8:15 p.m. ET
- Lions vs. Packers spread: Chargers -3.5
- Lions vs. Packers over-under: 52.5
- Lions vs. Packers moneyline: Chargers -190, Raiders +160
- Lions vs. Packers TV coverage: ESPN
Which Fantasy Football sleepers, breakouts and busts should you target and fade? And which QB shocks the NFL with a top-five performance? Join SportsLine now to get 2021 Fantasy Football cheat sheets for every single position, all from the model that called Josh Allen's huge season.
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