Mize (6-10) allowed seven runs on seven hits, two walks and a hit batsman while striking out one over four innings to take the loss versus the Diamondbacks on Friday.
Pena (wrist) is starting at shortstop and batting leadoff for Thursday night's matchup against the Athletics, Brian McTaggart of MLB.com reports.
The Astros selected Barrosa from Triple-A Sugar Land on Thursday.
The Astros designated Alexander for assignment Thursday.
The Astros placed Varsho on the 10-day injured list Thursday, retroactive to Wednesday, due to left wrist inflammation.
Pena (wrist) stole a base as a pinch runner in Wednesday's 6-5 extra-inning loss to the Mariners.
Hader (4-2) took the loss Wednesday against the Mariners, allowing two runs (one earned) on two hits and four walks across 1.1 innings.
Diaz went 2-for-5 with a two-run home run and an RBI triple in Wednesday's 6-5 extra-inning loss to the Mariners.
Pecko allowed three runs on four hits and two walks while striking out two over 2.2 innings in a no-decision versus the Mariners on Wednesday.
Tatis went 3-for-5 with a double and a run scored in Wednesday's 5-1 win over the Dodgers.
| PITCHING | INN | W | K | HA | ER | BBI | |
| C. Javier | Cristian Javier | 4.6 | 0.19 | 3.7 | 3.7 | 1.8 | 1.5 |
| Relievers | Relievers | 4.0 | 0.3 | 4.6 | 3.6 | 1.8 | 1.8 |
| HITTING | H | R | RBI | TB | BB | SB | |
| J. Pena | Jeremy Pena | 1.27 | 0.77 | 0.52 | 2.19 | 0.3 | 0.14 |
| Y. Alvarez | Yordan Alvarez | 1.23 | 0.68 | 0.76 | 2.41 | 0.77 | 0.02 |
| I. Paredes | Isaac Paredes | 0.98 | 0.46 | 0.6 | 1.76 | 0.46 | 0.0 |
| J. Altuve | Jose Altuve | 0.94 | 0.55 | 0.43 | 1.57 | 0.37 | 0.04 |
| T. Trammell | Taylor Trammell | 0.88 | 0.48 | 0.47 | 1.48 | 0.42 | 0.06 |
| C. Walker | Christian Walker | 0.9 | 0.51 | 0.58 | 1.76 | 0.31 | 0.01 |
| D. Varsho | Daulton Varsho | 0.87 | 0.5 | 0.46 | 1.67 | 0.38 | 0.08 |
| Y. Diaz | Yainer Diaz | 0.97 | 0.41 | 0.53 | 1.7 | 0.13 | 0.01 |
| L. Wade | LaMonte Wade | 0.68 | 0.35 | 0.42 | 1.06 | 0.58 | 0.01 |
KEY PLAYER INJURIESB. Matthews, M. Burrows, C. Correa, B. Walter NOT PROJECTED TO START:Christian Vazquez, Nick Allen, Cam Smith, Jake Meyers Batting order and lineup confirmed and provided by Rotowire. | |||||||
| PITCHING |
| Cristian Javier |
| Relievers |
| HITTING |
| Jeremy Pena |
| Yordan Alvarez |
| Isaac Paredes |
| Jose Altuve |
| Taylor Trammell |
| Christian Walker |
| Daulton Varsho |
| Yainer Diaz |
| LaMonte Wade |
| INN | W | K | HA | ER | BBI |
| 4.6 | 0.19 | 3.7 | 3.7 | 1.8 | 1.5 |
| 4.0 | 0.3 | 4.6 | 3.6 | 1.8 | 1.8 |
| H | R | RBI | TB | BB | SB |
| 1.27 | 0.77 | 0.52 | 2.19 | 0.3 | 0.14 |
| 1.23 | 0.68 | 0.76 | 2.41 | 0.77 | 0.02 |
| 0.98 | 0.46 | 0.6 | 1.76 | 0.46 | 0.0 |
| 0.94 | 0.55 | 0.43 | 1.57 | 0.37 | 0.04 |
| 0.88 | 0.48 | 0.47 | 1.48 | 0.42 | 0.06 |
| 0.9 | 0.51 | 0.58 | 1.76 | 0.31 | 0.01 |
| 0.87 | 0.5 | 0.46 | 1.67 | 0.38 | 0.08 |
| 0.97 | 0.41 | 0.53 | 1.7 | 0.13 | 0.01 |
| 0.68 | 0.35 | 0.42 | 1.06 | 0.58 | 0.01 |
