Lowe went 1-for-3 with a solo home run and a walk Thursday against the Brewers.
Soto allowed three hits and one earned run while striking out three across one inning Thursday against the Brewers.
Ashcraft (11-5) took the loss Thursday against the Brewers, allowing four runs on four hits and one walk while striking out five over five innings.
Mikolas (3-9) took the loss Thursday against the Phillies, allowing six runs on 12 hits and a walk across five innings. He struck out one.
Mlodzinski will start Friday's game against the Mets, Jose Negron of DK Pittsburgh Sports reports.
The Nationals paused Early's (elbow) throwing program Thursday after he felt forearm tightness during his latest live BP session, Danielle Allentuck of The Washington Post reports.
Lile is not in the lineup for Thursday's contest in Philadelphia.
The Nationals claimed Mills off waivers from the Dodgers on Thursday and optioned him to Triple-A Rochester.
Herz (elbow) will resume his rehab assignment with Single-A Fredericksburg on Saturday, Spencer Nusbaum of The Athletic reports.
Valdez is not in the lineup for Thursday's game in Milwaukee.
