Flores went 2-for-5 with a pair of home runs and six total RBI in Thursday's 13-1 win over Miami.
Ashcraft (12-5) earned the win in a complete game Thursday against the Marlins, allowing a run on three hits and a walk. He struck out 10.
The Pirates optioned Sisk to Triple-A Indianapolis on Thursday.
The Pirates recalled Mattson from Triple-A Indianapolis on Thursday.
The Pirates recalled Brannigan from Triple-A Indianapolis on Thursday.
The Pirates placed Rodriguez on the 10-day injured list Thursday with left hip inflammation.
Simon is not in the lineup for Thursday's contest in Miami.
Rodriguez (hip) remains out of the lineup for Thursday's game in Miami.
Sanchez went 2-for-4 with a home run and an RBI double in Wednesday's 4-3 extra-innings loss to the Padres.
Gonzales went 2-for-3 with a double and two runs scored in Wednesday's 8-2 defeat to the Marlins.
