Perez didn't factor into the decision Sunday against Houston, striking out two while allowing one run on six hits and two walks in 4.1 innings.
Dodd struck out the side to notch the save Sunday against Houston.
Lowder (6-12) took the loss Sunday against the Cubs, allowing five runs on six hits and three walks across three innings. He struck out three.
Riley is out of the lineup for Sunday's matchup with the Astros.
Cincinnati designated Friedl for assignment Sunday.
The Reds placed Burns on the 15-day injured list Sunday due to a right groin strain.
Cincinnati promoted Spiers from Triple-A Louisville on Sunday.
Pagan walked one and struck out one in a scoreless ninth inning Friday to record his 24th save of the season in a 6-4 win over the Cubs.
Burns didn't factor into the decision in Friday's 6-4 win over the Cubs, giving up two runs on four hits and two walks over three innings. He struck out four.
De La Cruz went 2-for-2 with two walks, a stolen base and two runs scored in Friday's 6-4 win over the Cubs.
