The Cardinals are starting basically their ideal lineup and their best pitcher in Adam Wainwright. The Brewers, still not hitting much, probably won't have star closer Josh Hader after back-to-back outings and Manager Craig Counsell already has confirmed setup man Devin Williams is not available. The Cards have their full pen after Wednesday's game vs. Kansas City was rained out. Runline at -160.

The Brewers travel after the Orioles game for their home opener in a 4:15 local time matinee. Not only do they have the quick turnaround but they also have all the pregame Opening Day festivities to get through. The Cardinals had yesterday off so all their top bullpen arms were able to rest. Devin Williams, Brad Boxberger, and Josh Hader are the three top Brewers bullpen arms and they all pitched each of the last two nights. Brandon Woodruff struggled in his first start allowing 7 ER in 3.2 IP against the Cubs. Adam Wainwright pitched 6 scoreless in his first start. The Cardinals were 11-8 overall against the Brewers last season and 7-3 in Milwaukee. Take the value in the Cardinals on the road.